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Colli-Pee: An innovative solution for non-invasive urine collection and preservation
Colli-Pee®, the heart of the company, is a patented award-winning urine collection device. Colli-Pee® allows for volumetric and standardized first-void urine collection and preservation. Urine collected with a Colli-Pee® offers improved diagnostic accuracy and patient comfort compared to a regular urine cup. The platform consists of variants collecting different volumes (4 mL to 40 mL*) for various application purposes.
"The non-invasive character of urine sampling, with option of home collection, will definitely help to enroll underserved women in cervical cancer screening and follow-up programs across the world."
Professor Alex Vorsters
Department of Vaccine & Infectious Disease, University of Antwerp, Belgium
- How does Colli-Pee® work
- Benefits of urine sampling with Colli-Pee®
- Urine stability
- Volume variants
- Home collection kits
- Application areas
How does Colli-Pee® work?
- Unscrew the cap
- Screw/ push the collector tube on the Colli-Pee® housing
- Collect urine. The device will automatically collect the correct volume
- Disconnect the connector tube from the Colli-Pee® housing
- Close the tube tightly, with the cap
- Dispose the Colli-Pee® and wash your hands
View the instructions for use
Colli-Pee® FV-5020 Colli-Pee® FV-5010 Colli-Pee® FV-5004 Colli-Pee® FV-5040
Benefits of urine sampling with Colli-Pee®
Urine sampling offers several benefits, however, not all urine fractions are the same. First-void urine is generally considered the first 20 mL to 30 mL of urine flow. This fraction contains higher concentrations of analytes associated with Human Papillomavirus (HPV) and Chlamydia trachomatis (CT) DNA than subsequent fractions. Additionally, first-void urine sampling is important to identify cancer biomarkers, such as prostate cancer.
Collecting a first-void urine sample with a standard urine cup can be awkward, messy and inconvenient for the user. For this reason, Novosanis developed Colli-Pee®.
Read more about the importance of first-void urine collection
Urine stability
Urinary analytes are susceptible to enzymatic and chemical degradation. Additionally, in the time between urine collection and processing, analytes can be degraded. Consequently, methods to stabilize urine samples are necessary. The Colli-Pee® device architecture enables immediate mixing of the sample with a urine preservative, improving stability of the urine specimen.
Colli-Pee® can be prefilled with Novosanis’ UCM® , to allow preservation of DNA in urine. Colli-Pee® UCM® has been CE-IVD marked and has been registered in several countries outside of Europe.
To extend the preservation coverage to other analytes (cfDNA, EV, EV RNA) a new preservative, UASTM has been developed. UASTM is available in Large Volumes format for research use only: Colli-Pee® UASTM FV-5040-RUO. Contact us to know more.
Optimal preservative to sample ratio depends on the type of preservative.
Our data shows:
- UCM® - 1:3 Preservative to sample ratio for optimal preservation performance
- UASTM - 2:5 Preservative to sample ratio for optimal preservation performance
Read more about our urine stabilization solutions
Volume variants
Colli-Pee® Regular Volumes
Colli-Pee® FV-5020 allows for standardized and volumetric urine collection of the first 20 mL of urine flow. This has applications in infectious diseases and oncology. Collector tubes can be pre-filled with a preservative for different urinary analytes, improving transport and storage of urine at room temperature.
Download Colli-Pee® Spec Sheet
Data sheet - Colli-Pee® FV-5020
Data sheet - Colli-Pee® UCM® FV-5020
Colli-Pee® Small Volumes
Colli-Pee® Small Volumes tubes are compatible with high-throughput instruments and can streamline the pre-analytical process, shorten turnaround time, minimize errors as well as reduce costs. Colli-Pee® FV-5010 and Colli-Pee® FV-5004 allow for standardized and volumetric urine collection of respectively the first 10 mL or 4 mL of urine flow. Collector tubes can be pre-filled with a preservative for different urinary analytes, improving transport and storage of urine at room temperature.
Download Colli-Pee® Small Volumes Flyer
Data Sheet - Colli-Pee® FV-5010
Data Sheet - Colli-Pee® UCM® FV-5010
Data Sheet - Colli-Pee® UAS® FV-5010-RUO
Data Sheet - Colli-Pee® FV-5004
Data Sheet - Colli-Pee® UCM® FV-5004
Colli-Pee® Large Volumes
For detection and monitoring of cancers, as well as new biomarker development, a larger volume of urine can be required. Additionally, Colli-Pee® Large Volumes supports multiomics research. Colli-Pee® FV-5040 allows for standardized and volumetric urine collection of the first 40 mL of urine flow. Collector tubes can be pre-filled with a preservative for different urinary analytes, improving transport and storage of urine at room temperature.
Data sheet Colli-Pee® UASTM FV-5040-RUO
Contact us for more information
Home-based collection kits
Novosanis is working on Colli-Pee® in a box for easy home-based urine collection. The kit allows postal delivery at home, next to postal shipment of the urine sample to the lab.
Discover more about Colli-Pee® in a box for home collection
*Some Novosanis products are in development or not available in all geographic regions. Contact us to know the registration status in your region.