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Colli-Pee: An innovative solution for non-invasive urine collection and stabilization
Colli-Pee®, the heart of the company, is a patented award-winning urine collection device. Colli-Pee® allows for volumetric and standardized urine collection including first-void urine. Urine collected with a Colli-Pee® offers improved diagnostic accuracy and patient comfort compared to a regular urine cup. The platform consists of variants collecting different volumes (4 mL to 45 mL*) for various application purposes.
- How does Colli-Pee work
- Benefits of urine sampling with Colli-Pee
- Urine stability
- Volume variants
- Home collection kits
- Application areas
How does Colli-Pee work?
- Unscrew the tube cap
- Screw the collector tube on the Colli-Pee® device
- Collect urine. The device will automatically collect the correct volume
- Disconnect the connector tube from the Colli-Pee® device
- Close the tube tightly, with the tube cap
- Dispose the Colli-Pee® and wash your hands
View the instructions for use
Colli-Pee 20mL Colli-Pee Small Volumes
Benefits of urine sampling with Colli-Pee
Urine sampling offers several benefits, however, not all urine fractions are the same. First-void urine is generally considered the first 20mL to 30mL of urine flow. This fraction contains higher concentrations of analytes associated with Human Papillomavirus (HPV) and Chlamydia trachomatis (CT) DNA than subsequent fractions. Additionally, first-void urine sampling is important to identify cancer biomarkers, such as prostate cancer.
Collecting a first-void urine sample with a standard urine cup can be awkward, messy and inconvenient for the user. For this reason, Novosanis developed Colli-Pee®.
Read more about the importance of first-void urine collection
Urine stability
Urinary analytes are susceptible to enzymatic and chemical degradation. Additionally, in the time between urine collection and processing, analytes can be degraded. Consequently, methods to stabilize urine samples are necessary. The Colli-Pee® device architecture enables immediate mixing of the sample with a urine preservative, improving stability of the urine specimen.
Colli-Pee® can be prefilled with Novosanis’ Urine Conservation Medium (UCM), to allow preservation of DNA in urine. Colli-Pee with UCM has been CE-IVD marked, and has been registered in several countries outside of Europe.
To extend the preservation coverage to other analytes (RNA, EV, cfDNA) a new preservative, Urinary Analyte Stabilizer (UAS) is currently in development.
Prototypes are available for evaluation purposes. Contact us to know more.
Optimal preservative to sample ratio depends on the type of preservative.
Our data shows:
- UCM - 1:3 Preservative to sample ratio for optimal preservation performance
- UAS - 4:10 Preservative to sample ratio for optimal preservation performance
Read more about our urine stabilization solutions
Volume variants
Colli-Pee 20 mL
Colli-Pee® 20 mL allows for standardized and volumetric urine collection of the first 20mL of urine flow. This has applications in infectious diseases and oncology. Collector tubes can be pre-filled with a preservative for different urinary analytes, improving transport and storage of urine at room temperature.
Data sheet - Colli-Pee 20 mL with UCM
Colli-Pee Small Volumes
Colli-Pee® Small Volumes tubes are compatible with high-throughput instruments and can streamline the pre-analytical process, shorten turnaround time, minimize errors as well as reduce costs. Collector tubes can be pre-filled with a preservative for different urinary analytes, improving transport and storage of urine at room temperature.
Download Colli-Pee Small Volumes Flyer
Data Sheet - Colli-Pee Small Volumes
Data Sheet - Colli-Pee Small Volumes with UCM
Colli-Pee Large Volumes
For detection and monitoring of cancers, as well as new biomarker development, a larger volume of urine can be required. Additionally, Colli-Pee® Large Volumes supports multi-omics research. Collector tubes can be pre-filled with a preservative for different urinary analytes, improving transport and storage of urine at room temperature.
Currently, the Colli-Pee Large Volumes variant is in development.
Contact us for more information
Home-based collection kits
Novosanis is working on Colli-Pee® in a box for easy home-based urine collection. The kit allows postal delivery at home, next to postal shipment of the urine sample to the lab.
Discover more about Colli-Pee in a box for home collection
*Some Novosanis products are in development or not available in all geographic regions. Contact us to know the registration status in your region.
