Ertik et al, 2021
Aim: To evaluate the clinical performance (sensitivity for high-grade CIN) of a dry vaginal self-sampling FLOQSwabs, the Evalyn Brush and the first-void Colli-Pee device containing UCM preservative compared to a physician taken sample with a PCR-based high-risk HPV (hrHPV) test.
Affiliations: Department of Gynaecology and Obstetrics, Hannover Medical School, 30625 Hannover, Germany, IZD Hannover, 30159 Hannover, Germany
Summary: A total of 65 female patients between 24-76 years of age were enrolled in the CoCoss trial. The study showed that all invasive cancer cases and over 90% of the CIN3+ cervical cancer lesions were found to be hrHPV positive with all three self-collection devices as compared to a physician taken PAP smear. In addition, participants considered all self-sampling devices as easy-to-use without any difficulties following the written instructions.