Imaging study

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29/04/2015

Aim: Measurement of skin thickness to characterize required needle length for intradermal vaccination using VAX-ID™

Partners: University of Antwerp (Pharmaceutical Sciences), Novosanis nv

  • 100 healthy adults included aged 18 to 65
  • Measurement of skin thickness at the deltoid region, the dorsal (PDF) and ventral side (PVF) of the proximal forearm
  • Determining the influence of personal characteristics, such as gender; BMI, age, on skin thickness

Conclusion: Significant differences in skin thickness were seen for the PVF, PDF and deltoid region for gender, and BMI. Age only influenced the skin thickness at deltoid region. A needle length of 1.0mm is best option for intradermal injection at the dorsal forearm.

High frequency ultrasound to assess skin thickness in healthy adults.pdf