Determination of the optimal first-void urine collection volume for the detection of viral and host biomarkers, and evaluation of an internal control. CASUS study

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Teblick et al, IPVC 2020 (Poster)  

Aim: To investigate whether the first-void collection volume has an effect on the detection of human and viral DNA endpoints and evaluate different DNA extraction protocols. 

Partners: Novosanis, Self-Screen, VAXINFECTIO University of Antwerp, Amsterdam UMC 

Results: The different collection volumes showed good concordance for hrHPV positivity on the HPV Risk assay. In addition, no significant differences were observed for human DNA endpoints (Beta-globin, GAPDH and ACTB) between different collection volumes.